Protein Details: Gap junction beta-7 protein

Protein ID

ICDB_Pro_1095

Protein Name

Gap junction beta-7 protein

Gene Name

GJB7; CX25

Organism

Homo sapiens (Human)

Length

223 amino acids

AlphaFoldDB

AF-Q6PEY0-F1-model_v4.pdb

Function

Sequence

MSWMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCKNVCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYHEGREKRHRKKLYVSPGTMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKCDLKPCPNTVDCFISKPTEKTIFILFLVITSCLCIVLNFIELSFLVLKCFIKCCLQKYLKKPQVLSV

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Intellectual Developmental Disorder;X-Linked

Location

Weakly expressed in placenta

DOI ID

10.1515/bc.2002.076; 10.1038/ng1285; 10.1038/nature02055; 10.1101/gr.2596504; 10.3109/15419060109080718; 10.1080/15419060302063

RefSeq

NP_940970.1; XP_005248773.1